5t37: Difference between revisions

No edit summary
No edit summary
 
(2 intermediate revisions by the same user not shown)
Line 1: Line 1:
'''Unreleased structure'''


The entry 5t37 is ON HOLD  until Paper Publication
==crystal structure of mPGES-1 bound to inhibitor==
<StructureSection load='5t37' size='340' side='right'caption='[[5t37]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5t37]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T37 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5T37 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.761&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=758:2-CHLORO-5-{[(2,2-DIMETHYLPROPANOYL)AMINO]METHYL}-N-(1H-IMIDAZOL-2-YL)BENZAMIDE'>758</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5t37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t37 OCA], [https://pdbe.org/5t37 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5t37 RCSB], [https://www.ebi.ac.uk/pdbsum/5t37 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5t37 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PTGES_HUMAN PTGES_HUMAN] Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).<ref>PMID:18682561</ref>


Authors: Luz, J.G., Antonysamy, S., Partridge, K., Fisher, M.
==See Also==
 
*[[Prostaglandin E synthase|Prostaglandin E synthase]]
Description: crystal structure of mPGES-1 bound to inhibitor
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Fisher, M]]
__TOC__
[[Category: Luz, J.G]]
</StructureSection>
[[Category: Partridge, K]]
[[Category: Homo sapiens]]
[[Category: Antonysamy, S]]
[[Category: Large Structures]]
[[Category: Antonysamy S]]
[[Category: Fisher M]]
[[Category: Luz JG]]
[[Category: Partridge K]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA