5rvy: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5rvy is ON HOLD
+==PanDDA analysis group deposition -- Crystal Structure of DHTKD1 in complex with Z437516460==
+<StructureSection load='5rvy' size='340' side='right'caption='[[5rvy]], [[Resolution|resolution]] 1.61&Aring;' scene=''>
-Authors: Bezerra, G.A., Foster, W.R., Bailey, H.J., Shrestha, L., Krojer, T., Brandao-Neto, J., Douangamath, A., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Yue, W.W.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5rvy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5RVY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5RVY FirstGlance]. <br>
-Description: PanDDA analysis group deposition --Crystal Structure of DHTKD1 in complex with Z437516460
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.609&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NWY:N-[(6-methylpyridin-3-yl)methyl]cyclobutanecarboxamide'>NWY</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr>
-[[Category: Foster, W.R]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5rvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5rvy OCA], [https://pdbe.org/5rvy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5rvy RCSB], [https://www.ebi.ac.uk/pdbsum/5rvy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5rvy ProSAT]</span></td></tr>
-[[Category: Bailey, H.J]]
+</table>
-[[Category: Arrowsmith, C.H]]
+== Disease ==
-[[Category: Burgess-Brown, N]]
+[https://www.uniprot.org/uniprot/DHTK1_HUMAN DHTK1_HUMAN] 2-aminoadipic 2-oxoadipic aciduria;Autosomal dominant Charcot-Marie-Tooth disease type 2Q. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.
-[[Category: Brandao-Neto, J]]
+== Function ==
-[[Category: Shrestha, L]]
+[https://www.uniprot.org/uniprot/DHTK1_HUMAN DHTK1_HUMAN] The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
-[[Category: Bezerra, G.A]]
+__TOC__
-[[Category: Edwards, A]]
+</StructureSection>
-[[Category: Douangamath, A]]
+[[Category: Homo sapiens]]
-[[Category: Krojer, T]]
+[[Category: Large Structures]]
-[[Category: Yue, W.W]]
+[[Category: Arrowsmith CH]]
-[[Category: Von Delft, F]]
+[[Category: Bailey HJ]]
-[[Category: Bountra, C]]
+[[Category: Bezerra GA]]
+[[Category: Bountra C]]
+[[Category: Brandao-Neto J]]
+[[Category: Burgess-Brown N]]
+[[Category: Douangamath A]]
+[[Category: Edwards A]]
+[[Category: Foster WR]]
+[[Category: Krojer T]]
+[[Category: Shrestha L]]
+[[Category: Yue WW]]
+[[Category: Von Delft F]]