5k4d: Difference between revisions
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New page: '''Unreleased structure''' The entry 5k4d is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures |
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==Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 3== | |||
<StructureSection load='5k4d' size='340' side='right'caption='[[5k4d]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5k4d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Nasonia_vitripennis Nasonia vitripennis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K4D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5K4D FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5k4d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k4d OCA], [https://pdbe.org/5k4d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5k4d RCSB], [https://www.ebi.ac.uk/pdbsum/5k4d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5k4d ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/EIF3D_NASVI EIF3D_NASVI] mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.[HAMAP-Rule:MF_03003] | |||
==See Also== | |||
*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Nasonia vitripennis]] | |||
[[Category: Cate JHD]] | |||
[[Category: Doudna JA]] | |||
[[Category: Kranzusch PJ]] | |||
[[Category: Lee ASY]] | |||
Latest revision as of 15:39, 6 March 2024
Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 3Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 3
Structural highlights
FunctionEIF3D_NASVI mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.[HAMAP-Rule:MF_03003] See Also |
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