5iy7: Difference between revisions
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==Human holo-PIC in the open state== | |||
<SX load='5iy7' size='340' side='right' viewer='molstar' caption='[[5iy7]], [[Resolution|resolution]] 8.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5iy7]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IY7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IY7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5iy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iy7 OCA], [https://pdbe.org/5iy7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5iy7 RCSB], [https://www.ebi.ac.uk/pdbsum/5iy7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5iy7 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/T2EB_HUMAN T2EB_HUMAN] Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. | |||
==See Also== | |||
*[[Helicase 3D structures|Helicase 3D structures]] | |||
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | |||
[[Category: | *[[TATA-binding protein 3D structures|TATA-binding protein 3D structures]] | ||
[[Category: | *[[Transcription initiation factors 3D structures|Transcription initiation factors 3D structures]] | ||
[[Category: | __TOC__ | ||
[[Category: He | </SX> | ||
[[Category: Ivanov | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Fang J]] | ||
[[Category: | [[Category: He Y]] | ||
[[Category: Inouye C]] | |||
[[Category: Ivanov I]] | |||
[[Category: Nogales E]] | |||
[[Category: Tjian R]] | |||
[[Category: Yan C]] | |||
Latest revision as of 15:35, 6 March 2024
Human holo-PIC in the open stateHuman holo-PIC in the open state
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