5do7: Difference between revisions
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==Crystal Structure of the Human Sterol Transporter ABCG5/ABCG8== | ==Crystal Structure of the Human Sterol Transporter ABCG5/ABCG8== | ||
<StructureSection load='5do7' size='340' side='right' caption='[[5do7]], [[Resolution|resolution]] 3.93Å' scene=''> | <StructureSection load='5do7' size='340' side='right'caption='[[5do7]], [[Resolution|resolution]] 3.93Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5do7]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DO7 OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5do7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DO7 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.93Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5do7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5do7 OCA], [https://pdbe.org/5do7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5do7 RCSB], [https://www.ebi.ac.uk/pdbsum/5do7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5do7 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Disease == | == Disease == | ||
[ | [https://www.uniprot.org/uniprot/ABCG5_HUMAN ABCG5_HUMAN] Sitosterolemia. The disease is caused by mutations affecting the gene represented in this entry. | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ABCG5_HUMAN ABCG5_HUMAN] Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. | ||
==See Also== | |||
*[[ABC transporter 3D structures|ABC transporter 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Borek | [[Category: Homo sapiens]] | ||
[[Category: Cohen | [[Category: Large Structures]] | ||
[[Category: Grishin | [[Category: Borek DM]] | ||
[[Category: Hobbs | [[Category: Cohen JC]] | ||
[[Category: Kinch | [[Category: Grishin NV]] | ||
[[Category: Lee | [[Category: Hobbs HH]] | ||
[[Category: Otwinowski | [[Category: Kinch LN]] | ||
[[Category: Rosenbaum | [[Category: Lee J-Y]] | ||
[[Category: Urbatsch | [[Category: Otwinowski Z]] | ||
[[Category: Xie | [[Category: Rosenbaum DM]] | ||
[[Category: Urbatsch IL]] | |||
[[Category: Xie X-S]] | |||
Latest revision as of 15:25, 6 March 2024
Crystal Structure of the Human Sterol Transporter ABCG5/ABCG8Crystal Structure of the Human Sterol Transporter ABCG5/ABCG8
Structural highlights
DiseaseABCG5_HUMAN Sitosterolemia. The disease is caused by mutations affecting the gene represented in this entry. FunctionABCG5_HUMAN Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. See Also |
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