5rkn: Difference between revisions
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==PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z373768900== | ==PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z373768900== | ||
<StructureSection load='5rkn' size='340' side='right'caption='[[5rkn]]' scene=''> | <StructureSection load='5rkn' size='340' side='right'caption='[[5rkn]], [[Resolution|resolution]] 1.23Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5RKN OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5rkn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5RKN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5RKN FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.23Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NUA:N-(1-ethyl-1H-pyrazol-4-yl)cyclobutanecarboxamide'>NUA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5rkn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5rkn OCA], [https://pdbe.org/5rkn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5rkn RCSB], [https://www.ebi.ac.uk/pdbsum/5rkn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5rkn ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PHIP_HUMAN PHIP_HUMAN] Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization.<ref>PMID:12242307</ref> <ref>PMID:21834987</ref> | |||
==See Also== | |||
*[[WD-repeat protein 3D structures|WD-repeat protein 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Aimon A]] | [[Category: Aimon A]] |