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==Crystal Structure of Untagged C54A Mutant Flavin Reductase (DszD) in Complex with FMN From Mycobacterium goodii== | |||
<StructureSection load='3pft' size='340' side='right'caption='[[3pft]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3pft]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_goodii Mycobacterium goodii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PFT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PFT FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.601Å</td></tr> | |||
== | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr> | ||
[[3pft]] is a 2 chain structure | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pft OCA], [https://pdbe.org/3pft PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pft RCSB], [https://www.ebi.ac.uk/pdbsum/3pft PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pft ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DSZD_MYCGD DSZD_MYCGD] An NADH:FMN oxidoreductase which supplies reduced FMN for the '4S' desulfurization pathway that removes covalently bound sulfur from dibenzothiophene (DBT) without breaking carbon-carbon bonds. Can also use FAD. Provides DszC and probably also DszA (DBT-monooxygenase and DBTO2-monooxygenase respectively) with reduced flavin (FMN and/or FAD).<ref>PMID:19144512</ref> | |||
==See Also== | ==See Also== | ||
*[[Flavin reductase|Flavin reductase]] | *[[Flavin reductase|Flavin reductase]] | ||
[[Category: | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium goodii]] | [[Category: Mycobacterium goodii]] | ||
[[Category: Gu | [[Category: Gu L]] | ||
[[Category: Li | [[Category: Li B]] | ||
[[Category: Li | [[Category: Li N]] | ||
[[Category: Li | [[Category: Li Q]] | ||
[[Category: Liu | [[Category: Liu S]] | ||
[[Category: Liu | [[Category: Liu X]] | ||
[[Category: Ma | [[Category: Ma C]] | ||
[[Category: Su | [[Category: Su J]] | ||
[[Category: Xu | [[Category: Xu P]] | ||
[[Category: Zhang | [[Category: Zhang C]] | ||
Latest revision as of 16:31, 1 March 2024
Crystal Structure of Untagged C54A Mutant Flavin Reductase (DszD) in Complex with FMN From Mycobacterium goodiiCrystal Structure of Untagged C54A Mutant Flavin Reductase (DszD) in Complex with FMN From Mycobacterium goodii
Structural highlights
FunctionDSZD_MYCGD An NADH:FMN oxidoreductase which supplies reduced FMN for the '4S' desulfurization pathway that removes covalently bound sulfur from dibenzothiophene (DBT) without breaking carbon-carbon bonds. Can also use FAD. Provides DszC and probably also DszA (DBT-monooxygenase and DBTO2-monooxygenase respectively) with reduced flavin (FMN and/or FAD).[1] See AlsoReferences
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