7tim: Difference between revisions

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-[[Image:7tim.png|left|200px]]
-{{STRUCTURE_7tim|  PDB=7tim  |  SCENE=  }}
+==STRUCTURE OF THE TRIOSEPHOSPHATE ISOMERASE-PHOSPHOGLYCOLOHYDROXAMATE COMPLEX: AN ANALOGUE OF THE INTERMEDIATE ON THE REACTION PATHWAY==
+<StructureSection load='7tim' size='340' side='right'caption='[[7tim]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-===STRUCTURE OF THE TRIOSEPHOSPHATE ISOMERASE-PHOSPHOGLYCOLOHYDROXAMATE COMPLEX: AN ANALOGUE OF THE INTERMEDIATE ON THE REACTION PATHWAY===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7tim]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TIM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TIM FirstGlance]. <br>
-{{ABSTRACT_PUBMED_2043623}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGH:PHOSPHOGLYCOLOHYDROXAMIC+ACID'>PGH</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tim OCA], [https://pdbe.org/7tim PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tim RCSB], [https://www.ebi.ac.uk/pdbsum/7tim PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tim ProSAT]</span></td></tr>
-[[7tim]] is a 2 chain structure of [[TIM test]] and [[Triose Phosphate Isomerase]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TIM OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TPIS_YEAST TPIS_YEAST]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ti/7tim_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=7tim ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[TIM test|TIM test]]
+*[[Triose phosphate isomerase 3D structures|Triose phosphate isomerase 3D structures]]
-*[[Triose Phosphate Isomerase|Triose Phosphate Isomerase]]
+__TOC__
+</StructureSection>
-==Reference==
+[[Category: Large Structures]]
-<ref group="xtra">PMID:002043623</ref><ref group="xtra">PMID:014636602</ref><ref group="xtra">PMID:017381236</ref><references group="xtra"/>
 [[Category: Saccharomyces cerevisiae]]
-[[Category: Triose-phosphate isomerase]]
+[[Category: Bash PA]]
-[[Category: Bash, P A.]]
+[[Category: Davenport RC]]
-[[Category: Davenport, R C.]]
+[[Category: Karplus M]]
-[[Category: Karplus, M.]]
+[[Category: Petsko GA]]
-[[Category: Petsko, G A.]]
+[[Category: Ringe D]]
-[[Category: Ringe, D.]]
+[[Category: Seaton BA]]
-[[Category: Seaton, B A.]]
-[[Category: Intramolecular oxidoreductase]]