4yff: Difference between revisions

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'''Unreleased structure'''


The entry 4yff is ON HOLD
==TNNI3K complexed with inhibitor 2==
<StructureSection load='4yff' size='340' side='right'caption='[[4yff]], [[Resolution|resolution]] 3.07&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4yff]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YFF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YFF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.07&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4CV:3-[(5-BROMO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)AMINO]-N-METHYL-4-(MORPHOLIN-4-YL)BENZENESULFONAMIDE'>4CV</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yff FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yff OCA], [https://pdbe.org/4yff PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yff RCSB], [https://www.ebi.ac.uk/pdbsum/4yff PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yff ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/TNI3K_HUMAN TNI3K_HUMAN] The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/TNI3K_HUMAN TNI3K_HUMAN] May play a role in cardiac physiology.<ref>PMID:12721663</ref>


Authors: Shewchuk, L.M., Wang, L., Lawhorn, B.G.
==See Also==
 
*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]]
Description: TNNI3K complexed with inhibitor 2
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Wang, L]]
__TOC__
[[Category: Lawhorn, B.G]]
</StructureSection>
[[Category: Shewchuk, L.M]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Lawhorn BG]]
[[Category: Shewchuk LM]]
[[Category: Wang L]]

Latest revision as of 16:03, 1 March 2024

TNNI3K complexed with inhibitor 2TNNI3K complexed with inhibitor 2

Structural highlights

4yff is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.07Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

TNI3K_HUMAN The disease is caused by mutations affecting the gene represented in this entry.

Function

TNI3K_HUMAN May play a role in cardiac physiology.[1]

See Also

References

  1. ↑ Zhao Y, Meng XM, Wei YJ, Zhao XW, Liu DQ, Cao HQ, Liew CC, Ding JF. Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I. J Mol Med. 2003 May;81(5):297-304. Epub 2003 Apr 30. PMID:12721663 doi:http://dx.doi.org/10.1007/s00109-003-0427-x

4yff, resolution 3.07Å

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