4y95: Difference between revisions

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-'''Unreleased structure'''
-The entry 4y95 is ON HOLD
+==Crystal structure of the kinase domain of Bruton's tyrosine kinase with mutations in the activation loop==
+<StructureSection load='4y95' size='340' side='right'caption='[[4y95]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4y95]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y95 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y95 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.599&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=746:4-TERT-BUTYL-N-[2-METHYL-3-(4-METHYL-6-{[4-(MORPHOLIN-4-YLCARBONYL)PHENYL]AMINO}-5-OXO-4,5-DIHYDROPYRAZIN-2-YL)PHENYL]BENZAMIDE'>746</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y95 OCA], [https://pdbe.org/4y95 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y95 RCSB], [https://www.ebi.ac.uk/pdbsum/4y95 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y95 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q3ZC95_BOVIN Q3ZC95_BOVIN]
-Authors: Wang, Q., Rosen, C.E., Kuriyan, J.
+==See Also==
+*[[Tyrosine kinase 3D structures|Tyrosine kinase 3D structures]]
-Description:
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Kuriyan, J]]
+[[Category: Bos taurus]]
-[[Category: Wang, Q]]
+[[Category: Large Structures]]
-[[Category: Rosen, C.E]]
+[[Category: Kuriyan J]]
+[[Category: Rosen CE]]
+[[Category: Wang Q]]