4x4l: Difference between revisions
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==Structure of human ALDH1A1 with inhibitor CM037== | |||
<StructureSection load='4x4l' size='340' side='right'caption='[[4x4l]], [[Resolution|resolution]] 1.85Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4x4l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X4L FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3XG:ETHYL+({4-OXO-3-[3-(PYRROLIDIN-1-YL)PROPYL]-3,4-DIHYDRO[1]BENZOTHIENO[3,2-D]PYRIMIDIN-2-YL}SULFANYL)ACETATE'>3XG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=YB:YTTERBIUM+(III)+ION'>YB</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x4l OCA], [https://pdbe.org/4x4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x4l RCSB], [https://www.ebi.ac.uk/pdbsum/4x4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x4l ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/AL1A1_HUMAN AL1A1_HUMAN] Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity). | |||
==See Also== | |||
*[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Hurley | [[Category: Homo sapiens]] | ||
[[Category: Morgan | [[Category: Large Structures]] | ||
[[Category: Hurley TD]] | |||
[[Category: Morgan CA]] | |||
Latest revision as of 15:59, 1 March 2024
Structure of human ALDH1A1 with inhibitor CM037Structure of human ALDH1A1 with inhibitor CM037
Structural highlights
FunctionAL1A1_HUMAN Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity). See Also |
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