4v48: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4v48]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1p86 1p86] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1p87 1p87]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V48 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V48 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4v48]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1p86 1p86] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1p87 1p87]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V48 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V48 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v48 OCA], [https://pdbe.org/4v48 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v48 RCSB], [https://www.ebi.ac.uk/pdbsum/4v48 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v48 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 11.5Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v48 OCA], [https://pdbe.org/4v48 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v48 RCSB], [https://www.ebi.ac.uk/pdbsum/4v48 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v48 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/RL2_ECOLI RL2_ECOLI] One of the primary rRNA binding proteins. Located near the base of the L1 stalk, it is probably also mobile. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is highly controversial.[HAMAP-Rule:MF_01320_B] In the E.coli 70S ribosome in the initiation state it has been modeled to make several contacts with the 16S rRNA (forming bridge B7b, PubMed:12809609); these contacts are broken in the model with bound EF-G.[HAMAP-Rule:MF_01320_B] | [https://www.uniprot.org/uniprot/RL2_ECOLI RL2_ECOLI] One of the primary rRNA binding proteins. Located near the base of the L1 stalk, it is probably also mobile. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is highly controversial.[HAMAP-Rule:MF_01320_B] In the E.coli 70S ribosome in the initiation state it has been modeled to make several contacts with the 16S rRNA (forming bridge B7b, PubMed:12809609); these contacts are broken in the model with bound EF-G.[HAMAP-Rule:MF_01320_B] | ||
==See Also== | ==See Also== | ||
*[[Ribosome 3D structures|Ribosome 3D structures]] | *[[Ribosome 3D structures|Ribosome 3D structures]] | ||
*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]] | *[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]] | ||
__TOC__ | __TOC__ | ||
</SX> | </SX> | ||