4nmh: Difference between revisions

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 ==11-beta-HSD1 in complex with a 3,3-Di-methyl-azetidin-2-one==
-<StructureSection load='4nmh' size='340' side='right' caption='[[4nmh]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
+<StructureSection load='4nmh' size='340' side='right'caption='[[4nmh]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4nmh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NMH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NMH FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4nmh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NMH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NMH FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2KG:(4S)-4-(2-METHOXYPHENYL)-3,3-DIMETHYL-1-[3-(METHYLSULFONYL)PHENYL]AZETIDIN-2-ONE'>2KG</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Hsd11b1, Hsd11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2KG:(4S)-4-(2-METHOXYPHENYL)-3,3-DIMETHYL-1-[3-(METHYLSULFONYL)PHENYL]AZETIDIN-2-ONE'>2KG</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/11-beta-hydroxysteroid_dehydrogenase 11-beta-hydroxysteroid dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.146 1.1.1.146] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nmh OCA], [https://pdbe.org/4nmh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nmh RCSB], [https://www.ebi.ac.uk/pdbsum/4nmh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nmh ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nmh OCA], [http://pdbe.org/4nmh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nmh RCSB], [http://www.ebi.ac.uk/pdbsum/4nmh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nmh ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/DHI1_MOUSE DHI1_MOUSE]] Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone.
+[https://www.uniprot.org/uniprot/DHI1_MOUSE DHI1_MOUSE] Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone.
 ==See Also==
-*[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]]
+*[[Hydroxysteroid dehydrogenase 3D structures|Hydroxysteroid dehydrogenase 3D structures]]
 __TOC__
 </StructureSection>
-[[Category: 11-beta-hydroxysteroid dehydrogenase]]
+[[Category: Large Structures]]
-[[Category: Lk3 transgenic mice]]
+[[Category: Mus musculus]]
-[[Category: Augustin, M]]
+[[Category: Augustin M]]
-[[Category: Blake, C]]
+[[Category: Blake C]]
-[[Category: Ertan, A]]
+[[Category: Ertan A]]
-[[Category: Gerhardt, S]]
+[[Category: Gerhardt S]]
-[[Category: Kilgour, E K]]
+[[Category: Kilgour EK]]
-[[Category: Krapp, S]]
+[[Category: Krapp S]]
-[[Category: McCoull, W]]
+[[Category: McCoull W]]
-[[Category: Moore, J E]]
+[[Category: Moore JE]]
-[[Category: Newcombe, N J]]
+[[Category: Newcombe NJ]]
-[[Category: Ogg, D J]]
+[[Category: Ogg DJ]]
-[[Category: Packer, M J]]
+[[Category: Packer MJ]]
-[[Category: Rees, A]]
+[[Category: Rees A]]
-[[Category: Revill, J]]
+[[Category: Revill J]]
-[[Category: Scott, J S]]
+[[Category: Scott JS]]
-[[Category: Selmi, N]]
+[[Category: Selmi N]]
-[[Category: Steinbacher, S]]
+[[Category: Steinbacher S]]
-[[Category: Whittamore, P R.O]]
+[[Category: Whittamore PRO]]
-[[Category: Oxidoreductase]]
-[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]