4nln: Difference between revisions

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-{{STRUCTURE_4nln|  PDB=4nln  |  SCENE=  }}
-===Structure of human DNA polymerase beta complexed with nicked DNA containing a template 8BrG and incoming CTP===
-==Function==
+==Structure of human DNA polymerase beta complexed with nicked DNA containing a template 8BrG and incoming CTP==
-[[http://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN]] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>
+<StructureSection load='4nln' size='340' side='right'caption='[[4nln]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4nln]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NLN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NLN FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.261&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGM:8-BROMO-2-DEOXYGUANOSINE-5-MONOPHOSPHATE'>BGM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nln FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nln OCA], [https://pdbe.org/4nln PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nln RCSB], [https://www.ebi.ac.uk/pdbsum/4nln PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nln ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>
-==About this Structure==
+==See Also==
-[[4nln]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NLN OCA].
+*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
+== References ==
-==Reference==
+<references/>
-<references group="xtra"/><references/>
+__TOC__
-[[Category: Koag, M C.]]
+</StructureSection>
-[[Category: Lee, S.]]
+[[Category: Homo sapiens]]
-[[Category: Min, K.]]
+[[Category: Large Structures]]
-[[Category: Monzingo, A F.]]
+[[Category: Koag M-C]]
-[[Category: Dna binding]]
+[[Category: Lee S]]
-[[Category: Helix-turn-helix motif]]
+[[Category: Min K]]
-[[Category: Lyase-dna complex]]
+[[Category: Monzingo AF]]
-[[Category: Nucleotidyl transferase]]
-[[Category: Nucleus]]
-[[Category: Polymerase fold]]
-[[Category: Transferase]]