4mqu: Difference between revisions

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-'''Unreleased structure'''
-The entry 4mqu is ON HOLD
+==Human GKRP complexed to AMG-3969 and S6P==
+<StructureSection load='4mqu' size='340' side='right'caption='[[4mqu]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4mqu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MQU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MQU FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.22&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MG9:2-{4-[(2S)-4-[(6-AMINOPYRIDIN-3-YL)SULFONYL]-2-(PROP-1-YN-1-YL)PIPERAZIN-1-YL]PHENYL}-1,1,1,3,3,3-HEXAFLUOROPROPAN-2-OL'>MG9</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mqu OCA], [https://pdbe.org/4mqu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mqu RCSB], [https://www.ebi.ac.uk/pdbsum/4mqu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mqu ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/GCKR_HUMAN GCKR_HUMAN] Inhibits glucokinase by forming an inactive complex with this enzyme.
-Authors: St. Jean, D. J., Ashton, K. S., Bartberger, M. D., Chen, J., Chmait, S., Cupples, R., Galbreath, E., Helmering, J., Jordan, S. R., Liu, L.
+==See Also==
+*[[Glucokinase Regulatory Protein|Glucokinase Regulatory Protein]]
-Description: Human GKRP complexed to AMG-3969 and S6P
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Ashton KS]]
+[[Category: Bartberger MD]]
+[[Category: Chen J]]
+[[Category: Chmait S]]
+[[Category: Cupples R]]
+[[Category: Galbreath E]]
+[[Category: Helmering J]]
+[[Category: Jordan SR]]
+[[Category: Liu L]]
+[[Category: St Jean DJ]]