4mlk: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4mlk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydia_trachomatis_434/Bu Chlamydia trachomatis 434/Bu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MLK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MLK FirstGlance]. <br>
<table><tr><td colspan='2'>[[4mlk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydia_trachomatis_434/Bu Chlamydia trachomatis 434/Bu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MLK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MLK FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mlk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mlk OCA], [https://pdbe.org/4mlk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mlk RCSB], [https://www.ebi.ac.uk/pdbsum/4mlk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mlk ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.051&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mlk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mlk OCA], [https://pdbe.org/4mlk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mlk RCSB], [https://www.ebi.ac.uk/pdbsum/4mlk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mlk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[https://www.uniprot.org/uniprot/A0A0H3MCR9_CHLT2 A0A0H3MCR9_CHLT2]  
[https://www.uniprot.org/uniprot/A0A0H3MCR9_CHLT2 A0A0H3MCR9_CHLT2]  
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Chlamydia trachomatis is a major cause of various diseases, including blinding trachoma and pelvic inflammatory disease, and is the leading reported sexually transmitted bacterial infection worldwide. All pathogenic Chlamydiae spp. utilize a supramolecular syringe, or type III secretion system (T3SS), to inject proteins into their obligate host in order to propagate infection. Here, the structure of CT584, a T3SS-associated protein, that has been refined to a resolution of 3.05 A is reported. The CT584 structure is a hexamer comprised of a trimer of dimers. The structure shares a high degree of similarity to the recently reported structure of an orthologous protein, Cpn0803, from Chlamydia pneumoniae, which highlights the highly conserved nature of this protein across these chlamydial species, despite different tissue tropism and disease pathology.
Structure of CT584 from Chlamydia trachomatis refined to 3.05 A resolution.,Barta ML, Hickey J, Kemege KE, Lovell S, Battaile KP, Hefty PS Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Nov;69(Pt 11):1196-201., doi: 10.1107/S1744309113027371. Epub 2013 Oct 26. PMID:24192348<ref>PMID:24192348</ref>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 4mlk" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Latest revision as of 15:27, 1 March 2024

3.05A resolution structure of CT584 from Chlamydia trachomatis3.05A resolution structure of CT584 from Chlamydia trachomatis

Structural highlights

4mlk is a 1 chain structure with sequence from Chlamydia trachomatis 434/Bu. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.051Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

A0A0H3MCR9_CHLT2

4mlk, resolution 3.05Å

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OCA
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