4mb8: Difference between revisions

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{{STRUCTURE_4mb8|  PDB=4mb8  |  SCENE=  }}
===Evolutionary history and metabolic insights of ancient mammalian uricases===
{{ABSTRACT_PUBMED_24550457}}


==Function==
==Evolutionary history and metabolic insights of ancient mammalian uricases==
[[http://www.uniprot.org/uniprot/URIC_CANFA URIC_CANFA]] Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.  
<StructureSection load='4mb8' size='340' side='right'caption='[[4mb8]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4mb8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Unclassified_Mammalia Unclassified Mammalia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MB8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MB8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4009&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mb8 OCA], [https://pdbe.org/4mb8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mb8 RCSB], [https://www.ebi.ac.uk/pdbsum/4mb8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mb8 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/URIC_CANLF URIC_CANLF] Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.


==About this Structure==
==See Also==
[[4mb8]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MB8 OCA].
*[[Urate oxidase 3D structures|Urate oxidase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:024550457</ref><references group="xtra"/><references/>
[[Category: Large Structures]]
[[Category: Factor independent urate hydroxylase]]
[[Category: Unclassified Mammalia]]
[[Category: Murphy, M N.]]
[[Category: Murphy MN]]
[[Category: Ortlund, E O.]]
[[Category: Ortlund EO]]
[[Category: Lysozome]]
[[Category: Oxidoreductase]]
[[Category: Uric acid oxidase]]

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