4m83: Difference between revisions

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'''Unreleased structure'''


The entry 4m83 is ON HOLD
==Ensemble refinement of protein crystal structure (2IYF) of macrolide glycosyltransferases OleD complexed with UDP and Erythromycin A==
<StructureSection load='4m83' size='340' side='right'caption='[[4m83]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4m83]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_antibioticus Streptomyces antibioticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M83 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M83 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.698&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ERY:ERYTHROMYCIN+A'>ERY</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m83 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m83 OCA], [https://pdbe.org/4m83 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m83 RCSB], [https://www.ebi.ac.uk/pdbsum/4m83 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m83 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OLED_STRAT OLED_STRAT] Specifically inactivates oleandomycin via 2'-O-glycosylation using UDP-glucose.


Authors: Wang, F., Helmich, K.E., Xu, W., Singh, S., Olmos, Jr., J.L., Martinez III, E., Bingman, C.A., Thorson, J.S., Phillips Jr., G.N., Enzyme Discovery for Natural Product Biosynthesis (NatPro)
==See Also==
 
*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
Description: Ensemble refinement of protein crystal structure (2IYF) of macrolide glycosyltransferases OleD complexed with UDP and Erythromycin A
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Streptomyces antibioticus]]
[[Category: Bingman CA]]
[[Category: Helmich KE]]
[[Category: Martinez iii E]]
[[Category: Olmos Jr JL]]
[[Category: Phillips Jr GN]]
[[Category: Singh S]]
[[Category: Thorson JS]]
[[Category: Wang F]]
[[Category: Xu W]]

Latest revision as of 15:24, 1 March 2024

Ensemble refinement of protein crystal structure (2IYF) of macrolide glycosyltransferases OleD complexed with UDP and Erythromycin AEnsemble refinement of protein crystal structure (2IYF) of macrolide glycosyltransferases OleD complexed with UDP and Erythromycin A

Structural highlights

4m83 is a 2 chain structure with sequence from Streptomyces antibioticus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.698Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

OLED_STRAT Specifically inactivates oleandomycin via 2'-O-glycosylation using UDP-glucose.

See Also

4m83, resolution 1.70Å

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