4l77: Difference between revisions
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==P450cin Active Site Water: Implications for Substrate Binding and Solvent Accessibility== | |||
<StructureSection load='4l77' size='340' side='right'caption='[[4l77]], [[Resolution|resolution]] 1.38Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4l77]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Citrobacter_braakii Citrobacter braakii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L77 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L77 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.379Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CNL:1,3,3-TRIMETHYL-2-OXABICYCLO[2.2.2]OCTANE'>CNL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l77 OCA], [https://pdbe.org/4l77 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l77 RCSB], [https://www.ebi.ac.uk/pdbsum/4l77 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l77 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CINA_CITBR CINA_CITBR] Involved in the degradation of cineol (eucalyptol). Catalyzes the initial hydroxylation of cineole exclusively at the pro-R carbon to give the (S)-6beta-hydroxycineole. Cineole is the natural substrate of CinA. | |||
==See Also== | |||
*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Citrobacter braakii]] | |||
[[Category: Large Structures]] | |||
[[Category: Madrona Y]] | |||
[[Category: Poulos TL]] | |||
Latest revision as of 15:17, 1 March 2024
P450cin Active Site Water: Implications for Substrate Binding and Solvent AccessibilityP450cin Active Site Water: Implications for Substrate Binding and Solvent Accessibility
Structural highlights
FunctionCINA_CITBR Involved in the degradation of cineol (eucalyptol). Catalyzes the initial hydroxylation of cineole exclusively at the pro-R carbon to give the (S)-6beta-hydroxycineole. Cineole is the natural substrate of CinA. See Also |
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