4l65: Difference between revisions

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{{STRUCTURE_4l65|  PDB=4l65  |  SCENE=  }}
===Crystal structure of the Candida albicans Methionine Synthase in complex with 5-Methyl-Tetrahydrofolate and Methionine===
{{ABSTRACT_PUBMED_24524835}}


==Function==
==Crystal structure of the Candida albicans Methionine Synthase in complex with 5-Methyl-Tetrahydrofolate and Methionine==
[[http://www.uniprot.org/uniprot/METE_CANAL METE_CANAL]] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.[HAMAP-Rule:MF_00172]  
<StructureSection load='4l65' size='340' side='right'caption='[[4l65]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4l65]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans_SC5314 Candida albicans SC5314]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L65 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L65 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.31&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C2F:5-METHYL-5,6,7,8-TETRAHYDROFOLIC+ACID'>C2F</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l65 OCA], [https://pdbe.org/4l65 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l65 RCSB], [https://www.ebi.ac.uk/pdbsum/4l65 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l65 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/METE_CANAL METE_CANAL] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.[HAMAP-Rule:MF_00172]


==About this Structure==
==See Also==
[[4l65]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L65 OCA].
*[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:024524835</ref><references group="xtra"/><references/>
[[Category: Candida albicans SC5314]]
[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
[[Category: Large Structures]]
[[Category: Robertus, J D.]]
[[Category: Robertus JD]]
[[Category: Ubhi, D.]]
[[Category: Ubhi D]]
[[Category: Cobalamin-independent]]
[[Category: Dual tim barrel]]
[[Category: Fungal]]
[[Category: Methionine synthase]]
[[Category: Surface entropy reduction]]
[[Category: Transferase]]

Latest revision as of 15:17, 1 March 2024

Crystal structure of the Candida albicans Methionine Synthase in complex with 5-Methyl-Tetrahydrofolate and MethionineCrystal structure of the Candida albicans Methionine Synthase in complex with 5-Methyl-Tetrahydrofolate and Methionine

Structural highlights

4l65 is a 1 chain structure with sequence from Candida albicans SC5314. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.31Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

METE_CANAL Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.[HAMAP-Rule:MF_00172]

See Also

4l65, resolution 2.31Å

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