4l1a: Difference between revisions
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==Crystallographic study of multi-drug resistant HIV-1 protease Lopinavir complex: mechanism of drug recognition and resistance== | |||
<StructureSection load='4l1a' size='340' side='right'caption='[[4l1a]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4l1a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L1A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L1A FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AB1:N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE'>AB1</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l1a OCA], [https://pdbe.org/4l1a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l1a RCSB], [https://www.ebi.ac.uk/pdbsum/4l1a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l1a ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q000H7_9HIV1 Q000H7_9HIV1] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Human immunodeficiency virus 1]] | |||
[[Category: Large Structures]] | |||
[[Category: Brunzelle J]] | |||
[[Category: Dewdney T]] | |||
[[Category: Kovari I]] | |||
[[Category: Kovari L]] | |||
[[Category: Liu Z]] | |||
[[Category: Reiter S]] | |||
[[Category: Wang Y]] | |||
[[Category: Yedidi RS]] |
Latest revision as of 15:16, 1 March 2024
Structural highlights
Function |
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