4l1a: Difference between revisions

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'''Unreleased structure'''


The entry 4l1a is ON HOLD
==Crystallographic study of multi-drug resistant HIV-1 protease Lopinavir complex: mechanism of drug recognition and resistance==
 
<StructureSection load='4l1a' size='340' side='right'caption='[[4l1a]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
Authors: Liu, Zhigang, Yedidi, Ravikiran, Wang, Yong, Dewdney, Tamaria , Reiter, Samuel , Brunzelle, Joseph , Kovari, Iulia, Kovari, Ladislau
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4l1a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L1A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L1A FirstGlance]. <br>
Description: Crystallographic study of multi-drug resistant HIV-1 protease Lopinavir complex: mechanism of drug recognition and resistance
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AB1:N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE'>AB1</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l1a OCA], [https://pdbe.org/4l1a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l1a RCSB], [https://www.ebi.ac.uk/pdbsum/4l1a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l1a ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q000H7_9HIV1 Q000H7_9HIV1]
__TOC__
</StructureSection>
[[Category: Human immunodeficiency virus 1]]
[[Category: Large Structures]]
[[Category: Brunzelle J]]
[[Category: Dewdney T]]
[[Category: Kovari I]]
[[Category: Kovari L]]
[[Category: Liu Z]]
[[Category: Reiter S]]
[[Category: Wang Y]]
[[Category: Yedidi RS]]

Latest revision as of 15:16, 1 March 2024

Crystallographic study of multi-drug resistant HIV-1 protease Lopinavir complex: mechanism of drug recognition and resistanceCrystallographic study of multi-drug resistant HIV-1 protease Lopinavir complex: mechanism of drug recognition and resistance

Structural highlights

4l1a is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q000H7_9HIV1

4l1a, resolution 1.90Å

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OCA
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