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==Crystal structure of 1nt-5'-overhanging double-helical CCG-repetitive RNA 20mer complexed with RSS p19== | ==Crystal structure of 1nt-5'-overhanging double-helical CCG-repetitive RNA 20mer complexed with RSS p19== | ||
<StructureSection load='4knq' size='340' side='right' caption='[[4knq]], [[Resolution|resolution]] 1.82Å' scene=''> | <StructureSection load='4knq' size='340' side='right'caption='[[4knq]], [[Resolution|resolution]] 1.82Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4knq]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4knq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Tomato_bushy_stunt_virus Tomato bushy stunt virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KNQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KNQ FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id=' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4knq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4knq OCA], [https://pdbe.org/4knq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4knq RCSB], [https://www.ebi.ac.uk/pdbsum/4knq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4knq ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/P19_TBSVK P19_TBSVK] Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity). | ||
==See Also== | |||
*[[P19|P19]] | |||
*[[RNA silencing suppressor|RNA silencing suppressor]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Katorcha | [[Category: Tomato bushy stunt virus]] | ||
[[Category: Malinina | [[Category: Katorcha E]] | ||
[[Category: Popov | [[Category: Malinina L]] | ||
[[Category: Tamjar | [[Category: Popov AN]] | ||
[[Category: Tamjar J]] | |||
Latest revision as of 15:14, 1 March 2024
Crystal structure of 1nt-5'-overhanging double-helical CCG-repetitive RNA 20mer complexed with RSS p19Crystal structure of 1nt-5'-overhanging double-helical CCG-repetitive RNA 20mer complexed with RSS p19
Structural highlights
FunctionP19_TBSVK Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity). See Also |
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