4jls: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
New page: '''Unreleased structure''' The entry 4jls is ON HOLD Authors: Keough, D.T., Hockova, D., Rejman, D., Spacek, P., Vrbkova, S., Krecmerova, M., Eng, W.S., Jans, H., West, N.P., Naesens, L...
 
No edit summary
 
(6 intermediate revisions by the same user not shown)
Line 1: Line 1:
'''Unreleased structure'''


The entry 4jls is ON HOLD
==Crystal Structure of E. coli XGPRT in complex with (3R,4S)-4-(Guanin-9-yl)-3-hydroxypyrrolidin-1-N-ylacetylphosphonic acid==
<StructureSection load='4jls' size='340' side='right'caption='[[4jls]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4jls]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_str._K-12_substr._MDS42 Escherichia coli str. K-12 substr. MDS42]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JLS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JLS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3ZE:{2-[(3S,4R)-3-(2-AMINO-6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)-4-HYDROXYPYRROLIDIN-1-YL]-2-OXOETHYL}PHOSPHONIC+ACID'>3ZE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jls FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jls OCA], [https://pdbe.org/4jls PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jls RCSB], [https://www.ebi.ac.uk/pdbsum/4jls PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jls ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/XGPT_ECOLI XGPT_ECOLI] Acts on guanine, xanthine and to a lesser extent hypoxanthine.<ref>PMID:9100006</ref>


Authors: Keough, D.T., Hockova, D., Rejman, D., Spacek, P., Vrbkova, S., Krecmerova, M., Eng, W.S., Jans, H., West, N.P., Naesens, L.M.J., de Jersey, J., Guddat, L.W.
==See Also==
 
*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
Description: Crystal Structure of E. coli XGPRT in complex with 3R,4S)-4-(Guanin-9-yl)-3-hydroxypyrrolidin-1-N-ylacetylphosphonic acid
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli str. K-12 substr. MDS42]]
[[Category: Large Structures]]
[[Category: Eng WS]]
[[Category: Guddat LW]]
[[Category: Hockova D]]
[[Category: Jans H]]
[[Category: Keough DT]]
[[Category: Krecmerova M]]
[[Category: Naesens LMJ]]
[[Category: Rejman D]]
[[Category: Spacek P]]
[[Category: Vrbkova S]]
[[Category: West NP]]
[[Category: De Jersey J]]

Latest revision as of 15:04, 1 March 2024

Crystal Structure of E. coli XGPRT in complex with (3R,4S)-4-(Guanin-9-yl)-3-hydroxypyrrolidin-1-N-ylacetylphosphonic acidCrystal Structure of E. coli XGPRT in complex with (3R,4S)-4-(Guanin-9-yl)-3-hydroxypyrrolidin-1-N-ylacetylphosphonic acid

Structural highlights

4jls is a 8 chain structure with sequence from Escherichia coli str. K-12 substr. MDS42. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

XGPT_ECOLI Acts on guanine, xanthine and to a lesser extent hypoxanthine.[1]

See Also

References

  1. Vos S, de Jersey J, Martin JL. Crystal structure of Escherichia coli xanthine phosphoribosyltransferase. Biochemistry. 1997 Apr 8;36(14):4125-34. PMID:9100006 doi:10.1021/bi962640d

4jls, resolution 2.20Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA