4jf2: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4jf2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lacticaseibacillus_rhamnosus Lacticaseibacillus rhamnosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JF2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4jf2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lacticaseibacillus_rhamnosus Lacticaseibacillus rhamnosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JF2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PRF:7-DEAZA-7-AMINOMETHYL-GUANINE'>PRF</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PRF:7-DEAZA-7-AMINOMETHYL-GUANINE'>PRF</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jf2 OCA], [https://pdbe.org/4jf2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jf2 RCSB], [https://www.ebi.ac.uk/pdbsum/4jf2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jf2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jf2 OCA], [https://pdbe.org/4jf2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jf2 RCSB], [https://www.ebi.ac.uk/pdbsum/4jf2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jf2 ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
PreQ1 riboswitches regulate genes by binding the pyrrolopyrimidine intermediate preQ1 during the biosynthesis of the essential tRNA base queuosine. We report what is to our knowledge the first preQ1-II riboswitch structure at 2.3-A resolution, which uses a previously uncharacterized fold to achieve effector recognition at the confluence of a three-way helical junction flanking a pseudoknotted ribosome-binding site. The results account for translational control mediated by the preQ1-II riboswitch class and expand the known repertoire of ligand-binding modes used by regulatory RNAs.
Structure of a class II preQ riboswitch reveals ligand recognition by a new fold.,Liberman JA, Salim M, Krucinska J, Wedekind JE Nat Chem Biol. 2013 Apr 14. doi: 10.1038/nchembio.1231. PMID:23584677<ref>PMID:23584677</ref>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 4jf2" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Riboswitch 3D structures|Riboswitch 3D structures]]
*[[Riboswitch 3D structures|Riboswitch 3D structures]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Latest revision as of 15:03, 1 March 2024

Structure of a class II preQ1 riboswitch reveals ligand recognition by a new foldStructure of a class II preQ1 riboswitch reveals ligand recognition by a new fold

Structural highlights

4jf2 is a 1 chain structure with sequence from Lacticaseibacillus rhamnosus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.28Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

See Also

4jf2, resolution 2.28Å

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