4j81: Difference between revisions

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'''Unreleased structure'''


The entry 4j81 is ON HOLD
==Crystal structure of beta'-COP/Insig-1 complex==
 
<StructureSection load='4j81' size='340' side='right'caption='[[4j81]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
Authors: Ma, Wenfu, Goldberg, Jonathan
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4j81]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J81 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J81 FirstGlance]. <br>
Description: Crystal structure of beta' -COP/Insig-1 complex
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.745&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j81 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j81 OCA], [https://pdbe.org/4j81 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j81 RCSB], [https://www.ebi.ac.uk/pdbsum/4j81 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j81 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/COPB2_YEAST COPB2_YEAST] The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.<ref>PMID:17101773</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Goldberg J]]
[[Category: Ma W]]

Latest revision as of 15:02, 1 March 2024

Crystal structure of beta'-COP/Insig-1 complexCrystal structure of beta'-COP/Insig-1 complex

Structural highlights

4j81 is a 4 chain structure with sequence from Homo sapiens and Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.745Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

COPB2_YEAST The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.[1]

References

  1. ↑ Gabriely G, Kama R, Gerst JE. Involvement of specific COPI subunits in protein sorting from the late endosome to the vacuole in yeast. Mol Cell Biol. 2007 Jan;27(2):526-40. Epub 2006 Nov 13. PMID:17101773 doi:MCB.00577-06

4j81, resolution 1.75Å

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OCA
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