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==Crystal structure of p19 in complex with double-helical RNA 19mer p(CAG)3C(CCG)3== | ==Crystal structure of p19 in complex with double-helical RNA 19mer p(CAG)3C(CCG)3== | ||
<StructureSection load='4j5v' size='340' side='right' caption='[[4j5v]], [[Resolution|resolution]] 2.15Å' scene=''> | <StructureSection load='4j5v' size='340' side='right'caption='[[4j5v]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4j5v]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4j5v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Tomato_bushy_stunt_virus Tomato bushy stunt virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J5V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J5V FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id=' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j5v OCA], [https://pdbe.org/4j5v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j5v RCSB], [https://www.ebi.ac.uk/pdbsum/4j5v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j5v ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/P19_TBSVK P19_TBSVK] Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity). | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Tomato bushy stunt virus]] | ||
[[Category: | [[Category: Malinina L]] | ||
[[Category: | [[Category: Popov AN]] | ||
[[Category: | [[Category: Tamjar J]] | ||
Latest revision as of 15:01, 1 March 2024
Crystal structure of p19 in complex with double-helical RNA 19mer p(CAG)3C(CCG)3Crystal structure of p19 in complex with double-helical RNA 19mer p(CAG)3C(CCG)3
Structural highlights
FunctionP19_TBSVK Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity). See Also |
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