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{{STRUCTURE_4j5v|  PDB=4j5v  |  SCENE=  }}
===Crystal structure of p19 in complex with double-helical RNA 19mer p(CAG)3C(CCG)3===


==Function==
==Crystal structure of p19 in complex with double-helical RNA 19mer p(CAG)3C(CCG)3==
[[http://www.uniprot.org/uniprot/P19_TBSVK P19_TBSVK]] Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).  
<StructureSection load='4j5v' size='340' side='right'caption='[[4j5v]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4j5v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Tomato_bushy_stunt_virus Tomato bushy stunt virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J5V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J5V FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j5v OCA], [https://pdbe.org/4j5v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j5v RCSB], [https://www.ebi.ac.uk/pdbsum/4j5v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j5v ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/P19_TBSVK P19_TBSVK] Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).


==About this Structure==
==See Also==
[[4j5v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J5V OCA].
*[[P19|P19]]
[[Category: Malinina, L.]]
*[[RNA silencing suppressor|RNA silencing suppressor]]
[[Category: Popov, A N.]]
__TOC__
[[Category: Tamjar, J.]]
</StructureSection>
[[Category: Dimer]]
[[Category: Large Structures]]
[[Category: Rna binding protein-rna complex]]
[[Category: Tomato bushy stunt virus]]
[[Category: Rna silencing suppression]]
[[Category: Malinina L]]
[[Category: Trinucleotide repeat]]
[[Category: Popov AN]]
[[Category: Tamjar J]]

Latest revision as of 15:01, 1 March 2024

Crystal structure of p19 in complex with double-helical RNA 19mer p(CAG)3C(CCG)3Crystal structure of p19 in complex with double-helical RNA 19mer p(CAG)3C(CCG)3

Structural highlights

4j5v is a 2 chain structure with sequence from Tomato bushy stunt virus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.15Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

P19_TBSVK Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).

See Also

4j5v, resolution 2.15Å

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