4ilr: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
m Protected "4ilr" [edit=sysop:move=sysop]
No edit summary
 
(5 intermediate revisions by the same user not shown)
Line 1: Line 1:
'''Unreleased structure'''


The entry 4ilr is ON HOLD
==Recognition and Cleavage of a non-structured CRISPR RNA by its Processing Endoribonuclease Cas6==
<StructureSection load='4ilr' size='340' side='right'caption='[[4ilr]], [[Resolution|resolution]] 3.09&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ilr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ILR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ILR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.088&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ilr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ilr OCA], [https://pdbe.org/4ilr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ilr RCSB], [https://www.ebi.ac.uk/pdbsum/4ilr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ilr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CAS6B_SACS2 CAS6B_SACS2] CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease, generating an 8 base-long tag known as the 5' handle.<ref>PMID:21507944</ref>


Authors: Shao, Y,, Li, H
==See Also==
 
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
Description: Recognition and Cleavage of a non-structured CRISPR RNA by its Processing Endoribonuclease Cas6
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharolobus solfataricus P2]]
[[Category: Li H]]
[[Category: Shao Y]]

Latest revision as of 14:57, 1 March 2024

Recognition and Cleavage of a non-structured CRISPR RNA by its Processing Endoribonuclease Cas6Recognition and Cleavage of a non-structured CRISPR RNA by its Processing Endoribonuclease Cas6

Structural highlights

4ilr is a 1 chain structure with sequence from Saccharolobus solfataricus P2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.088Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CAS6B_SACS2 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease, generating an 8 base-long tag known as the 5' handle.[1]

See Also

References

  1. ↑ Lintner NG, Kerou M, Brumfield SK, Graham S, Liu H, Naismith JH, Sdano M, Peng N, She Q, Copie V, Young MJ, White MF, Lawrence CM. Structural and functional characterization of an archaeal clustered regularly interspaced short palindromic repeat (CRISPR)-associated complex for antiviral defense (CASCADE). J Biol Chem. 2011 Jun 17;286(24):21643-56. Epub 2011 Apr 20. PMID:21507944 doi:10.1074/jbc.M111.238485

4ilr, resolution 3.09Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=4ilr&oldid=4074276"