4gzc: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(4 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{STRUCTURE_4gzc|  PDB=4gzc  |  SCENE=  }}
===Crystal structure of yeast Ent2 ENTH domain===
{{ABSTRACT_PUBMED_23553749}}


==Function==
==Crystal structure of yeast Ent2 ENTH domain==
[[http://www.uniprot.org/uniprot/ENT2_YEAST ENT2_YEAST]] Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin.<ref>PMID:10449404</ref>
<StructureSection load='4gzc' size='340' side='right'caption='[[4gzc]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4gzc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GZC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GZC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gzc OCA], [https://pdbe.org/4gzc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gzc RCSB], [https://www.ebi.ac.uk/pdbsum/4gzc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gzc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ENT2_YEAST ENT2_YEAST] Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin.<ref>PMID:10449404</ref>  


==About this Structure==
==See Also==
[[4gzc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GZC OCA].
*[[Epsin|Epsin]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:023553749</ref><references group="xtra"/><references/>
__TOC__
[[Category: Saccharomyces cerevisiae s288c]]
</StructureSection>
[[Category: Costakes, G T.]]
[[Category: Large Structures]]
[[Category: Stauffacher, C V.]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Balbe]]
[[Category: Costakes GT]]
[[Category: Endocytosis]]
[[Category: Stauffacher CV]]
[[Category: Enth]]
[[Category: Lipid binding protein]]

Latest revision as of 14:35, 1 March 2024

Crystal structure of yeast Ent2 ENTH domainCrystal structure of yeast Ent2 ENTH domain

Structural highlights

4gzc is a 1 chain structure with sequence from Saccharomyces cerevisiae S288C. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.3Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ENT2_YEAST Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin.[1]

See Also

References

  1. ↑ Wendland B, Steece KE, Emr SD. Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis. EMBO J. 1999 Aug 16;18(16):4383-93. PMID:10449404 doi:10.1093/emboj/18.16.4383

4gzc, resolution 1.30Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=4gzc&oldid=4073904"