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==Crystal Structure of Rat Galectin-1 in Complex with Lactose== | ==Crystal Structure of Rat Galectin-1 in Complex with Lactose== | ||
<StructureSection load='4ga9' size='340' side='right' caption='[[4ga9]], [[Resolution|resolution]] 1.88Å' scene=''> | <StructureSection load='4ga9' size='340' side='right'caption='[[4ga9]], [[Resolution|resolution]] 1.88Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4ga9]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4ga9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GA9 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900008:alpha-lactose'>PRD_900008</scene></td></tr> | ||
< | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ga9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ga9 OCA], [https://pdbe.org/4ga9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ga9 RCSB], [https://www.ebi.ac.uk/pdbsum/4ga9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ga9 ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/LEG1_RAT LEG1_RAT] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates (By similarity). | ||
==See Also== | |||
*[[Galectin 3D structures|Galectin 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Rattus norvegicus]] | ||
[[Category: | [[Category: Hirsch JA]] | ||
[[Category: | [[Category: Segev O]] | ||
Latest revision as of 14:26, 1 March 2024
Crystal Structure of Rat Galectin-1 in Complex with LactoseCrystal Structure of Rat Galectin-1 in Complex with Lactose
Structural highlights
FunctionLEG1_RAT May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates (By similarity). See Also |
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