4ez8: Difference between revisions

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-{{STRUCTURE_4ez8|  PDB=4ez8  |  SCENE=  }}
-===Crystal structure of mouse thymidylate sythase in ternary complex with N(4)-hydroxy-2'-deoxycytidine-5'-monophosphate and the cofactor product, dihydrofolate===
-==Function==
+==Crystal structure of mouse thymidylate sythase in ternary complex with N(4)-hydroxy-2'-deoxycytidine-5'-monophosphate and the cofactor product, dihydrofolate==
-[[http://www.uniprot.org/uniprot/TYSY_MOUSE TYSY_MOUSE]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (By similarity).
+<StructureSection load='4ez8' size='340' side='right'caption='[[4ez8]], [[Resolution|resolution]] 1.17&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4ez8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EZ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EZ8 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.17&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DHF:DIHYDROFOLIC+ACID'>DHF</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NOH:2-DEOXY-N-HYDROXYCYTIDINE+5-(DIHYDROGEN+PHOSPHATE)'>NOH</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ez8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ez8 OCA], [https://pdbe.org/4ez8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ez8 RCSB], [https://www.ebi.ac.uk/pdbsum/4ez8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ez8 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TYSY_MOUSE TYSY_MOUSE] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (By similarity).
-==About this Structure==
+==See Also==
-[[4ez8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EZ8 OCA].
+*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Mus musculus]]
-[[Category: Thymidylate synthase]]
+[[Category: Banaszak K]]
-[[Category: Banaszak, K.]]
+[[Category: Dowiercial A]]
-[[Category: Dowiercial, A.]]
+[[Category: Gorecka K]]
-[[Category: Gorecka, K.]]
+[[Category: Jarmula A]]
-[[Category: Jarmula, A.]]
+[[Category: Kierdaszuk B]]
-[[Category: Kierdaszuk, B.]]
+[[Category: Rode W]]
-[[Category: Rode, W.]]
+[[Category: Rypniewski W]]
-[[Category: Rypniewski, W.]]
+[[Category: Wilk P]]
-[[Category: Wilk, P.]]
-[[Category: Dihydrofolic acid]]
-[[Category: Methyltransferase]]
-[[Category: Ternary complex]]
-[[Category: Transferase-transferase inhibitor complex]]