4ey2: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 4ey2 is ON HOLD  until Paper Publication
+==Crystal structure of NDM-1 bound to hydrolyzed methicillin==
+<StructureSection load='4ey2' size='340' side='right'caption='[[4ey2]], [[Resolution|resolution]] 1.17&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4ey2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EY2 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.17&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0RM:(2R,4S)-2-{(R)-CARBOXY[(2,6-DIMETHOXYBENZOYL)AMINO]METHYL}-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>0RM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ey2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ey2 OCA], [https://pdbe.org/4ey2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ey2 RCSB], [https://www.ebi.ac.uk/pdbsum/4ey2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ey2 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.
-Authors: Strynadka, N.C.J., King, D.T.
+==See Also==
+*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
-Description: Hydrolase 1c
+__TOC__
+</StructureSection>
+[[Category: Klebsiella pneumoniae]]
+[[Category: Large Structures]]
+[[Category: King DT]]
+[[Category: Strynadka NCJ]]