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{{STRUCTURE_4edk|  PDB=4edk  |  SCENE=  }}
===The structure of the S. aureus DnaG RNA Polymerase Domain bound to GTP and Manganese===
{{ABSTRACT_PUBMED_22795082}}


==Function==
==The structure of the S. aureus DnaG RNA Polymerase Domain bound to GTP and Manganese==
[[http://www.uniprot.org/uniprot/PRIM_STAAU PRIM_STAAU]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis.  
<StructureSection load='4edk' size='340' side='right'caption='[[4edk]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[4edk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EDK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EDK FirstGlance]. <br>
[[4edk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EDK OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4edk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4edk OCA], [https://pdbe.org/4edk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4edk RCSB], [https://www.ebi.ac.uk/pdbsum/4edk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4edk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DNAG_STAAU DNAG_STAAU] RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.[HAMAP-Rule:MF_00974]


==See Also==
==See Also==
*[[RNA polymerase|RNA polymerase]]
*[[Nerve growth factor|Nerve growth factor]]
 
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
==Reference==
__TOC__
<ref group="xtra">PMID:022795082</ref><references group="xtra"/><references/>
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Berger, J M.]]
[[Category: Berger JM]]
[[Category: Chu, C.]]
[[Category: Chu C]]
[[Category: Corn, J E.]]
[[Category: Corn JE]]
[[Category: Rymer, R U.]]
[[Category: Rymer RU]]
[[Category: Solorio, F A.]]
[[Category: Solorio FA]]
[[Category: Wang, J D.]]
[[Category: Wang JD]]
[[Category: Catalytic domain]]
[[Category: Nucleoside polyphosphate]]
[[Category: Nucleoside triphosphate]]
[[Category: Protein-ligand complex]]
[[Category: Transferase]]

Latest revision as of 14:03, 1 March 2024

The structure of the S. aureus DnaG RNA Polymerase Domain bound to GTP and ManganeseThe structure of the S. aureus DnaG RNA Polymerase Domain bound to GTP and Manganese

Structural highlights

4edk is a 1 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DNAG_STAAU RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.[HAMAP-Rule:MF_00974]

See Also

4edk, resolution 2.00Å

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