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==The structure of Escherichia coli SfsA==
==The structure of Escherichia coli SfsA==
<StructureSection load='4dap' size='340' side='right' caption='[[4dap]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4dap' size='340' side='right'caption='[[4dap]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4dap]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DAP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DAP FirstGlance]. <br>
<table><tr><td colspan='2'>[[4dap]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DAP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DAP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4da2|4da2]], [[4dav|4dav]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">sfsA, sfs1, b0146, JW0142 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dap OCA], [https://pdbe.org/4dap PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dap RCSB], [https://www.ebi.ac.uk/pdbsum/4dap PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dap ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dap OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dap RCSB], [http://www.ebi.ac.uk/pdbsum/4dap PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SFSA_ECOLI SFSA_ECOLI] Binds to DNA non-specifically. Could be a regulatory factor involved in maltose metabolism.<ref>PMID:2013578</ref> <ref>PMID:11272834</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Allen, F L.]]
[[Category: Large Structures]]
[[Category: Baker, P J.]]
[[Category: Allen FL]]
[[Category: Dna binding protein]]
[[Category: Baker PJ]]
[[Category: Nuclease]]
[[Category: Ob fold]]

Latest revision as of 13:43, 1 March 2024

The structure of Escherichia coli SfsAThe structure of Escherichia coli SfsA

Structural highlights

4dap is a 1 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SFSA_ECOLI Binds to DNA non-specifically. Could be a regulatory factor involved in maltose metabolism.[1] [2]

References

  1. ↑ Kawamukai M, Utsumi R, Takeda K, Higashi A, Matsuda H, Choi YL, Komano T. Nucleotide sequence and characterization of the sfs1 gene: sfs1 is involved in CRP*-dependent mal gene expression in Escherichia coli. J Bacteriol. 1991 Apr;173(8):2644-8. PMID:2013578
  2. ↑ Takeda K, Akimoto C, Kawamukai M. Effects of the Escherichia coli sfsA gene on mal genes expression and a DNA binding activity of SfsA. Biosci Biotechnol Biochem. 2001 Jan;65(1):213-7. PMID:11272834

4dap, resolution 2.20Å

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