3v98: Difference between revisions

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[[Image:3v98.png|left|200px]]


{{STRUCTURE_3v98|  PDB=3v98  |  SCENE=  }}
==S663D Stable-5-LOX==
 
<StructureSection load='3v98' size='340' side='right'caption='[[3v98]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
===S663D Stable-5-LOX===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3v98]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V98 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V98 FirstGlance]. <br>
{{ABSTRACT_PUBMED_22516296}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.07&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v98 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v98 OCA], [https://pdbe.org/3v98 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v98 RCSB], [https://www.ebi.ac.uk/pdbsum/3v98 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v98 ProSAT]</span></td></tr>
[[3v98]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V98 OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/LOX5_HUMAN LOX5_HUMAN] Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.<ref>PMID:21233389</ref>
<ref group="xtra">PMID:022516296</ref><references group="xtra"/>
== References ==
[[Category: Arachidonate 5-lipoxygenase]]
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bartlett, S G.]]
[[Category: Large Structures]]
[[Category: Boeglin, W E.]]
[[Category: Bartlett SG]]
[[Category: Brash, A R.]]
[[Category: Boeglin WE]]
[[Category: Gilbert, N C.]]
[[Category: Brash AR]]
[[Category: Neau, D B.]]
[[Category: Gilbert NC]]
[[Category: Newcomer, M E.]]
[[Category: Neau DB]]
[[Category: Rui, Z.]]
[[Category: Newcomer ME]]
[[Category: Waight, M.]]
[[Category: Rui Z]]
[[Category: Dioxygenase]]
[[Category: Waight M]]
[[Category: Lipoxygenase]]
[[Category: Oxidoreductase]]

Latest revision as of 13:34, 1 March 2024

S663D Stable-5-LOXS663D Stable-5-LOX

Structural highlights

3v98 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.07Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LOX5_HUMAN Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.[1]

References

  1. ↑ Gilbert NC, Bartlett SG, Waight MT, Neau DB, Boeglin WE, Brash AR, Newcomer ME. The structure of human 5-lipoxygenase. Science. 2011 Jan 14;331(6014):217-9. PMID:21233389 doi:10.1126/science.1197203

3v98, resolution 2.07Å

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