3v8r: Difference between revisions
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==Crystal structure of NAD kinase 1 H223E mutant from Listeria monocytogenes in complex with 5'-amino-8-bromo-5'-deoxyadenosine== | |||
<StructureSection load='3v8r' size='340' side='right'caption='[[3v8r]], [[Resolution|resolution]] 2.39Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3v8r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V8R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V8R FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.39Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5NB:5-AMINO-8-BROMO-5-DEOXYADENOSINE'>5NB</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v8r OCA], [https://pdbe.org/3v8r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v8r RCSB], [https://www.ebi.ac.uk/pdbsum/3v8r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v8r ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NADK1_LISMO NADK1_LISMO] Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.[HAMAP-Rule:MF_00361]<ref>PMID:17686780</ref> <ref>PMID:22608967</ref> | |||
==See Also== | |||
*[[NAD kinase|NAD kinase]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Listeria monocytogenes]] | |||
[[Category: Assairi L]] | |||
[[Category: Dugu L]] | |||
[[Category: Dussurget O]] | |||
[[Category: Gelin M]] | |||
[[Category: Huteau V]] | |||
[[Category: Labesse G]] | |||
[[Category: Morellato L]] | |||
[[Category: Pochet S]] | |||
[[Category: Poncet-Montange G]] | |||