3v8p: Difference between revisions

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-[[Image:3v8p.png|left|200px]]
-<!--
+==Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a new di-adenosine inhibitor formed in situ==
-The line below this paragraph, containing "STRUCTURE_3v8p", creates the "Structure Box" on the page.
+<StructureSection load='3v8p' size='340' side='right'caption='[[3v8p]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3v8p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V8P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V8P FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2901&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZNB:2-[6-azanyl-9-[(2R,3R,4S,5R)-5-[[(azanylidene-$l^{4}-azanylidene)amino]methyl]-3,4-bis(oxidanyl)oxolan-2-yl]purin-8-yl]sulfanyl-N-[[(2R,3S,4R,5R)-5-(6-azanyl-8-bromanyl-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl]ethanamide'>ZNB</scene></td></tr>
-{{STRUCTURE_3v8p|  PDB=3v8p  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v8p OCA], [https://pdbe.org/3v8p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v8p RCSB], [https://www.ebi.ac.uk/pdbsum/3v8p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v8p ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NADK1_LISMO NADK1_LISMO] Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.[HAMAP-Rule:MF_00361]<ref>PMID:17686780</ref> <ref>PMID:22608967</ref>
-===Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a new di-adenosine inhibitor formed in situ===
+==See Also==
+*[[NAD kinase|NAD kinase]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_22608967}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 22608967 is the PubMed ID number.
+</StructureSection>
--->
+[[Category: Large Structures]]
-{{ABSTRACT_PUBMED_22608967}}
-==About this Structure==
-[[3v8p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V8P OCA].
-==Reference==
-<ref group="xtra">PMID:022608967</ref><references group="xtra"/>
 [[Category: Listeria monocytogenes]]
-[[Category: Assairi, L.]]
+[[Category: Assairi L]]
-[[Category: Dugu, L.]]
+[[Category: Dugu L]]
-[[Category: Dussurget, O.]]
+[[Category: Dussurget O]]
-[[Category: Gelin, M.]]
+[[Category: Gelin M]]
-[[Category: Huteau, V.]]
+[[Category: Huteau V]]
-[[Category: Labesse, G.]]
+[[Category: Labesse G]]
-[[Category: Morellato, L.]]
+[[Category: Morellato L]]
-[[Category: Pochet, S.]]
+[[Category: Pochet S]]
-[[Category: Poncet-Montange, G.]]
+[[Category: Poncet-Montange G]]
-[[Category: Inorganic polyphosphate/atp-nad kinase 1]]
-[[Category: Ligand-screening by crystallography]]
-[[Category: Transferase-transferase inhibitor complex]]
-[[Category: Two-domain kinase]]