3ull: Difference between revisions

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OCA

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 ==HUMAN MITOCHONDRIAL SINGLE-STRANDED DNA BINDING PROTEIN==
-<StructureSection load='3ull' size='340' side='right' caption='[[3ull]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+<StructureSection load='3ull' size='340' side='right'caption='[[3ull]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3ull]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ULL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ULL FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3ull]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ULL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ULL FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ull FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ull OCA], [http://pdbe.org/3ull PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ull RCSB], [http://www.ebi.ac.uk/pdbsum/3ull PDBsum]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ull FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ull OCA], [https://pdbe.org/3ull PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ull RCSB], [https://www.ebi.ac.uk/pdbsum/3ull PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ull ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/SSBP_HUMAN SSBP_HUMAN]] This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA replication. Associates with mitochondrial DNA.
+[https://www.uniprot.org/uniprot/SSBP_HUMAN SSBP_HUMAN] This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA replication. Associates with mitochondrial DNA.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ul/3ull_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ul/3ull_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
@@ Line 17: / Line 19: @@
 </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ull ConSurf].
 <div style="clear:both"></div>
-<div style="background-color:#fffaf0;">
-== Publication Abstract from PubMed ==
-We solved the crystal structure of the homotetrameric single-stranded DNA binding (SSB) protein from human mitochondria at a resolution of 2.4 A. The tetramer is formed by two dimers interacting head-to-head and shows D2 symmetry. Sequence-related tetrameric SSB proteins occur in prokaryotes and eukaryotic mitochondria; this is the first report of an atomic resolution structure of this type of protein. Using biochemical data and analysis of sequence homologies, we were able to correlate the functional properties with structure. We propose that ssDNA wraps around the tetrameric HsmtSSB protein through electropositive channels guided by flexible loops.
-Crystal structure of human mitochondrial single-stranded DNA binding protein at 2.4 A resolution.,Yang C, Curth U, Urbanke C, Kang C Nat Struct Biol. 1997 Feb;4(2):153-7. PMID:9033597<ref>PMID:9033597</ref>
-From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-</div>
-<div class="pdbe-citations 3ull" style="background-color:#fffaf0;"></div>
 ==See Also==
-*[[Single-stranded DNA-binding protein|Single-stranded DNA-binding protein]]
+*[[Single-stranded DNA-binding protein 3D structures|Single-stranded DNA-binding protein 3D structures]]
-== References ==
-<references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Curth, U]]
+[[Category: Large Structures]]
-[[Category: Kang, C]]
+[[Category: Curth U]]
-[[Category: Urbanke, C]]
+[[Category: Kang C]]
-[[Category: Yang, C]]
+[[Category: Urbanke C]]
-[[Category: Dna replication]]
+[[Category: Yang C]]
-[[Category: Dna-binding protein]]
-[[Category: Mitochondrion]]
-[[Category: Transit peptide]]