3ubt: Difference between revisions

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[[Image:3ubt.png|left|200px]]


{{STRUCTURE_3ubt|  PDB=3ubt  |  SCENE=  }}
==Crystal Structure of C71S Mutant of DNA Cytosine-5 Methyltransferase M.HaeIII Bound to DNA==
 
<StructureSection load='3ubt' size='340' side='right'caption='[[3ubt]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
===Crystal Structure of C71S Mutant of DNA Cytosine-5 Methyltransferase M.HaeIII Bound to DNA===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3ubt]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_aegyptius Haemophilus aegyptius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UBT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UBT FirstGlance]. <br>
{{ABSTRACT_PUBMED_23012373}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.502&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2PE:NONAETHYLENE+GLYCOL'>2PE</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ubt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ubt OCA], [https://pdbe.org/3ubt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ubt RCSB], [https://www.ebi.ac.uk/pdbsum/3ubt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ubt ProSAT]</span></td></tr>
[[3ubt]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_aegyptius Haemophilus aegyptius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UBT OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/MTH3_HAEAE MTH3_HAEAE] This methylase recognizes the double-stranded sequence GGCC, causes specific methylation on C-3 on both strands, and protects the DNA from cleavage by the HaeIII endonuclease.
__TOC__
</StructureSection>
[[Category: Haemophilus aegyptius]]
[[Category: Haemophilus aegyptius]]
[[Category: Didovyk, A.]]
[[Category: Large Structures]]
[[Category: Verdine, G L.]]
[[Category: Didovyk A]]
[[Category: Cytosine-5 dna methylation]]
[[Category: Verdine GL]]
[[Category: Dna binding]]
[[Category: Dna cytosine-5 methyltransferase]]
[[Category: Protein-dna complex]]
[[Category: S-adenosyl methionine binding]]
[[Category: Transferase-dna complex]]

Latest revision as of 13:19, 1 March 2024

Crystal Structure of C71S Mutant of DNA Cytosine-5 Methyltransferase M.HaeIII Bound to DNACrystal Structure of C71S Mutant of DNA Cytosine-5 Methyltransferase M.HaeIII Bound to DNA

Structural highlights

3ubt is a 9 chain structure with sequence from Haemophilus aegyptius. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.502Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MTH3_HAEAE This methylase recognizes the double-stranded sequence GGCC, causes specific methylation on C-3 on both strands, and protects the DNA from cleavage by the HaeIII endonuclease.

3ubt, resolution 2.50Å

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OCA
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