3u3o: Difference between revisions

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-[[Image:3u3o.png|left|200px]]
-<!--
+==Crystal structure of Human SULT1A1 bound to PAP and two 3-Cyano-7-hydroxycoumarin==
-The line below this paragraph, containing "STRUCTURE_3u3o", creates the "Structure Box" on the page.
+<StructureSection load='3u3o' size='340' side='right'caption='[[3u3o]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3u3o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U3O FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3QV:7-HYDROXY-2-OXO-2H-CHROMENE-3-CARBONITRILE'>3QV</scene>, <scene name='pdbligand=A3P:ADENOSINE-3-5-DIPHOSPHATE'>A3P</scene></td></tr>
-{{STRUCTURE_3u3o|  PDB=3u3o  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u3o OCA], [https://pdbe.org/3u3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u3o RCSB], [https://www.ebi.ac.uk/pdbsum/3u3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u3o ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ST1A1_HUMAN ST1A1_HUMAN] Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Has also estrogen sulfotransferase activity. responsible for the sulfonation and activation of minoxidil. Is Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.<ref>PMID:12471039</ref> <ref>PMID:16221673</ref>
-===Crystal structure of Human SULT1A1 bound to PAP and two 3-Cyano-7-hydroxycoumarin===
+==See Also==
+*[[Sulfotransferase 3D structures|Sulfotransferase 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_22069470}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 22069470 is the PubMed ID number.
+</StructureSection>
--->
-{{ABSTRACT_PUBMED_22069470}}
-==About this Structure==
-[[3u3o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U3O OCA].
-==Reference==
-<ref group="xtra">PMID:022069470</ref><references group="xtra"/>
-[[Category: Aryl sulfotransferase]]
 [[Category: Homo sapiens]]
-[[Category: Aharoni, A.]]
+[[Category: Large Structures]]
-[[Category: Berger, I.]]
+[[Category: Aharoni A]]
-[[Category: Guttman, C.]]
+[[Category: Berger I]]
-[[Category: Zarivach, R.]]
+[[Category: Guttman C]]
-[[Category: 3-cyano-7-hydroxycoumarin]]
+[[Category: Zarivach R]]
-[[Category: Arylsulfotransferase]]
-[[Category: Pap]]
-[[Category: Transferase]]
-[[Category: Xenobiotic]]