3tw8: Difference between revisions

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-[[Image:3tw8.png|left|200px]]
-<!--
+==GEF domain of DENND 1B in complex with Rab GTPase Rab35==
-The line below this paragraph, containing "STRUCTURE_3tw8", creates the "Structure Box" on the page.
+<StructureSection load='3tw8' size='340' side='right'caption='[[3tw8]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3tw8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TW8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TW8 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tw8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tw8 OCA], [https://pdbe.org/3tw8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tw8 RCSB], [https://www.ebi.ac.uk/pdbsum/3tw8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tw8 ProSAT]</span></td></tr>
-{{STRUCTURE_3tw8|  PDB=3tw8  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DEN1B_HUMAN DEN1B_HUMAN] Guanine nucleotide exchange factor (GEF) for RAB35. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. May play a role in clathrin-mediated endocytosis.<ref>PMID:20154091</ref> <ref>PMID:20937701</ref>
-===GEF domain of DENND 1B in complex with Rab GTPase Rab35===
+==See Also==
+*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
+*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
-<!--
+== References ==
-The line below this paragraph, {{ABSTRACT_PUBMED_22065758}}, adds the Publication Abstract to the page
+<references/>
-(as it appears on PubMed at http://www.pubmed.gov), where 22065758 is the PubMed ID number.
+__TOC__
--->
+</StructureSection>
-{{ABSTRACT_PUBMED_22065758}}
-==About this Structure==
-[[3tw8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TW8 OCA].
-==Reference==
-<ref group="xtra">PMID:022065758</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Kummel, D.]]
+[[Category: Large Structures]]
-[[Category: Reinisch, K M.]]
+[[Category: Kummel D]]
-[[Category: Wu, X D.]]
+[[Category: Reinisch KM]]
-[[Category: Guanine exchange factor]]
+[[Category: Wu XD]]
-[[Category: Longin domain]]
-[[Category: Protein transport]]
-[[Category: Rab gtpase]]