3tqb: Difference between revisions
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< | ==Structure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with folate== | ||
<StructureSection load='3tqb' size='340' side='right'caption='[[3tqb]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3tqb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Coxiella_burnetii Coxiella burnetii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TQB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TQB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |||
--> | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tqb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tqb OCA], [https://pdbe.org/3tqb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tqb RCSB], [https://www.ebi.ac.uk/pdbsum/3tqb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tqb ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q83AB2_COXBU Q83AB2_COXBU] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[PIRNR:PIRNR000194] | |||
== | ==See Also== | ||
*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[ | |||
[[Category: Coxiella burnetii]] | [[Category: Coxiella burnetii]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Cassidy | [[Category: Cassidy M]] | ||
[[Category: Franklin | [[Category: Franklin MC]] | ||
[[Category: Hillerich | [[Category: Hillerich B]] | ||
[[Category: Love | [[Category: Love J]] | ||
Latest revision as of 13:10, 1 March 2024
Structure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with folateStructure of the dihydrofolate reductase (folA) from Coxiella burnetii in complex with folate
Structural highlights
FunctionQ83AB2_COXBU Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[PIRNR:PIRNR000194] See Also |
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