3t5q: Difference between revisions

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[[Image:3t5q.png|left|200px]]


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==3A structure of Lassa virus nucleoprotein in complex with ssRNA==
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<StructureSection load='3t5q' size='340' side='right'caption='[[3t5q]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3t5q]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Mopeia_Lassa_virus_reassortant_29 Mopeia Lassa virus reassortant 29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T5Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T5Q FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
{{STRUCTURE_3t5q|  PDB=3t5q  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t5q OCA], [https://pdbe.org/3t5q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t5q RCSB], [https://www.ebi.ac.uk/pdbsum/3t5q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t5q ProSAT]</span></td></tr>
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== Function ==
[https://www.uniprot.org/uniprot/Q5S585_9VIRU Q5S585_9VIRU] Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses (By similarity).[PIRNR:PIRNR004029]


===3A structure of Lassa virus nucleoprotein in complex with ssRNA===
==See Also==
 
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
 
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==About this Structure==
[[3t5q]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Mopeia_lassa_reassortant_29 Mopeia lassa reassortant 29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T5Q OCA].
 
==Reference==
<ref group="xtra">PMID:022084115</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Mopeia lassa reassortant 29]]
[[Category: Large Structures]]
[[Category: Hastie, K M.]]
[[Category: Mopeia Lassa virus reassortant 29]]
[[Category: King, L B.]]
[[Category: Hastie KM]]
[[Category: Liu, T.]]
[[Category: King LB]]
[[Category: Ngo, N.]]
[[Category: Liu T]]
[[Category: Saphire, E O.]]
[[Category: Ngo N]]
[[Category: Torre, J C.de la.]]
[[Category: Saphire EO]]
[[Category: Woods, V L.]]
[[Category: Woods VL]]
[[Category: Zandonatti, M A.]]
[[Category: Zandonatti MA]]
[[Category: Single stranded rna]]
[[Category: De la Torre JC]]
[[Category: Ssrna]]
[[Category: Viral protein-rna complex]]

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