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==Crystal structure of Dipeptide Epimerase from Methylococcus capsulatus complexed with Mg and dipeptide L-Arg-D-Lys== | |||
<StructureSection load='3rit' size='340' side='right'caption='[[3rit]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3rit]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Methylococcus_capsulatus Methylococcus capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RIT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RIT FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.701Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=DLY:D-LYSINE'>DLY</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rit OCA], [https://pdbe.org/3rit PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rit RCSB], [https://www.ebi.ac.uk/pdbsum/3rit PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rit ProSAT]</span></td></tr> | ||
[[3rit]] is a 5 chain structure | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/KRDE_METCA KRDE_METCA] Catalyzes the epimerization of L-Lys-L-Arg to L-Lys-D-Arg. Can also catalyze the epimerization of other cationic dipeptides, such as L-Arg-L-Arg, L-Lys-L-Lys and L-Lys-L-His, but with lower efficiency (in vitro).<ref>PMID:22392983</ref> | |||
==See Also== | ==See Also== | ||
*[[Muconate cycloisomerase|Muconate cycloisomerase]] | *[[Muconate cycloisomerase|Muconate cycloisomerase]] | ||
== References == | |||
== | <references/> | ||
< | __TOC__ | ||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Methylococcus capsulatus]] | [[Category: Methylococcus capsulatus]] | ||
[[Category: Gerlt | [[Category: Gerlt JA]] | ||
[[Category: Lukk | [[Category: Lukk T]] | ||
[[Category: Nair | [[Category: Nair SK]] | ||
[[Category: Sakai | [[Category: Sakai A]] | ||
[[Category: Song | [[Category: Song L]] | ||
Latest revision as of 12:43, 1 March 2024
Crystal structure of Dipeptide Epimerase from Methylococcus capsulatus complexed with Mg and dipeptide L-Arg-D-LysCrystal structure of Dipeptide Epimerase from Methylococcus capsulatus complexed with Mg and dipeptide L-Arg-D-Lys
Structural highlights
FunctionKRDE_METCA Catalyzes the epimerization of L-Lys-L-Arg to L-Lys-D-Arg. Can also catalyze the epimerization of other cationic dipeptides, such as L-Arg-L-Arg, L-Lys-L-Lys and L-Lys-L-His, but with lower efficiency (in vitro).[1] See AlsoReferences
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