5r5y: Difference between revisions
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New page: '''Unreleased structure''' The entry 5r5y is ON HOLD Authors: Coker, J.A., Bezerra, G.A., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Yue, W.W., Marsden, B.D. Descript... |
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==PanDDA analysis group deposition -- Crystal Structure of FIBRINOGEN-LIKE GLOBE DOMAIN OF HUMAN TENASCIN-C in complex with Z509756472== | |||
<StructureSection load='5r5y' size='340' side='right'caption='[[5r5y]], [[Resolution|resolution]] 1.57Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5r5y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5R5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5R5Y FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.57Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JGG:N-[(4-cyanophenyl)methyl]morpholine-4-carboxamide'>JGG</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5r5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5r5y OCA], [https://pdbe.org/5r5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5r5y RCSB], [https://www.ebi.ac.uk/pdbsum/5r5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5r5y ProSAT]</span></td></tr> | ||
[[Category: Arrowsmith | </table> | ||
[[Category: Bezerra | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/TENA_HUMAN TENA_HUMAN] Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. | ||
[[Category: | __TOC__ | ||
[[Category: Edwards | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Arrowsmith CH]] | |||
[[Category: Bezerra GA]] | |||
[[Category: Bountra C]] | |||
[[Category: Coker JA]] | |||
[[Category: Edwards AM]] | |||
[[Category: Marsden BD]] | |||
[[Category: Yue WW]] | |||
[[Category: Von Delft F]] | |||
Latest revision as of 14:36, 21 February 2024
PanDDA analysis group deposition -- Crystal Structure of FIBRINOGEN-LIKE GLOBE DOMAIN OF HUMAN TENASCIN-C in complex with Z509756472PanDDA analysis group deposition -- Crystal Structure of FIBRINOGEN-LIKE GLOBE DOMAIN OF HUMAN TENASCIN-C in complex with Z509756472
Structural highlights
FunctionTENA_HUMAN Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. |
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