5qus: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| (One intermediate revision by the same user not shown) | |||
| Line 1: | Line 1: | ||
==HumRadA1 soaked with 5 mM indazole in 10% DMSO== | ==HumRadA1 soaked with 5 mM indazole in 10% DMSO== | ||
<StructureSection load='5qus' size='340' side='right'caption='[[5qus]]' scene=''> | <StructureSection load='5qus' size='340' side='right'caption='[[5qus]], [[Resolution|resolution]] 1.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QUS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QUS FirstGlance]. <br> | <table><tr><td colspan='2'>[[5qus]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QUS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QUS FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qus OCA], [https://pdbe.org/5qus PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qus RCSB], [https://www.ebi.ac.uk/pdbsum/5qus PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qus ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.247Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=LZ1:1H-INDAZOLE'>LZ1</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qus OCA], [https://pdbe.org/5qus PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qus RCSB], [https://www.ebi.ac.uk/pdbsum/5qus PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qus ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/RADA_PYRFU RADA_PYRFU] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Pyrococcus furiosus]] | |||
[[Category: Hyvonen M]] | [[Category: Hyvonen M]] | ||
[[Category: Marsh M]] | [[Category: Marsh M]] | ||
Latest revision as of 14:28, 21 February 2024
HumRadA1 soaked with 5 mM indazole in 10% DMSOHumRadA1 soaked with 5 mM indazole in 10% DMSO
Structural highlights
FunctionRADA_PYRFU Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. |
| ||||||||||||||||||