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==Structured Domain of Drosophila melanogaster Boca p65 2 2 Crystal form==
==Structured Domain of Drosophila melanogaster Boca p65 2 2 Crystal form==
<StructureSection load='3off' size='340' side='right' caption='[[3off]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3off' size='340' side='right'caption='[[3off]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3off]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OFF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OFF FirstGlance]. <br>
<table><tr><td colspan='2'>[[3off]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OFF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OFF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.002&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ofe|3ofe]], [[3ofg|3ofg]], [[3ofh|3ofh]], [[2i9s|2i9s]], [[2rqk|2rqk]], [[2rqm|2rqm]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3off FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3off OCA], [https://pdbe.org/3off PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3off RCSB], [https://www.ebi.ac.uk/pdbsum/3off PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3off ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">boca, CG30498 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3off FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3off OCA], [http://pdbe.org/3off PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3off RCSB], [http://www.ebi.ac.uk/pdbsum/3off PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3off ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MESD_DROME MESD_DROME]] Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wg pathway, since some LDLRs are coreceptors for the canonical Wnt pathway.  
[https://www.uniprot.org/uniprot/MESD_DROME MESD_DROME] Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wg pathway, since some LDLRs are coreceptors for the canonical Wnt pathway.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Drome]]
[[Category: Drosophila melanogaster]]
[[Category: Collins, M N]]
[[Category: Large Structures]]
[[Category: Hendrickson, W A]]
[[Category: Collins MN]]
[[Category: Chaperone]]
[[Category: Hendrickson WA]]
[[Category: Lrp]]
[[Category: Mesd]]
[[Category: Molecular chaperone]]
[[Category: Protein folding]]
[[Category: Ywtd propeller]]

Latest revision as of 14:16, 21 February 2024

Structured Domain of Drosophila melanogaster Boca p65 2 2 Crystal formStructured Domain of Drosophila melanogaster Boca p65 2 2 Crystal form

Structural highlights

3off is a 1 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.002Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MESD_DROME Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wg pathway, since some LDLRs are coreceptors for the canonical Wnt pathway.

3off, resolution 2.00Å

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