3cw4: Difference between revisions

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[[Image:3cw4.png|left|200px]]


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==Large c-terminal domain of influenza a virus RNA-dependent polymerase PB2==
The line below this paragraph, containing "STRUCTURE_3cw4", creates the "Structure Box" on the page.
<StructureSection load='3cw4' size='340' side='right'caption='[[3cw4]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3cw4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus Influenza A virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CW4 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cw4 OCA], [https://pdbe.org/3cw4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cw4 RCSB], [https://www.ebi.ac.uk/pdbsum/3cw4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cw4 ProSAT]</span></td></tr>
{{STRUCTURE_3cw4|  PDB=3cw4  |  SCENE=  }}
</table>
 
== Function ==
===Large c-terminal domain of influenza a virus RNA-dependent polymerase PB2===
[https://www.uniprot.org/uniprot/PB2_I34A1 PB2_I34A1] Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication (By similarity).
 
 
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{{ABSTRACT_PUBMED_19144639}}
 
==About this Structure==
[[3cw4]] is a 1 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CW4 OCA].  


==See Also==
==See Also==
*[[RNA polymerase]]
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
*[[User:Michael Strong/H1N1]]
__TOC__
*[[User:Michael Strong/H1N1/PB2]]
</StructureSection>
*[[User:Michael Strong/H1N1/PB2/MSA]]
[[Category: Influenza A virus]]
 
[[Category: Large Structures]]
==Reference==
[[Category: Fujiki H]]
<ref group="xtra">PMID:019144639</ref><references group="xtra"/>
[[Category: Horita T]]
[[Category: Influenza a virus]]
[[Category: Kise D]]
[[Category: Fujiki, H.]]
[[Category: Kuzuhara T]]
[[Category: Horita, T.]]
[[Category: Murasaki Y]]
[[Category: Kise, D.]]
[[Category: Tsuge H]]
[[Category: Kuzuhara, T.]]
[[Category: Utsunomiya H]]
[[Category: Murasaki, Y.]]
[[Category: Yoshida H]]
[[Category: Tsuge, H.]]
[[Category: Utsunomiya, H.]]
[[Category: Yoshida, H.]]
[[Category: Mitochondrion]]
[[Category: Mrna capping]]
[[Category: Mrna processing]]
[[Category: Nucleus]]
[[Category: Rna polymerase]]
[[Category: Transferase]]
[[Category: Virion]]

Latest revision as of 14:16, 21 February 2024

Large c-terminal domain of influenza a virus RNA-dependent polymerase PB2Large c-terminal domain of influenza a virus RNA-dependent polymerase PB2

Structural highlights

3cw4 is a 1 chain structure with sequence from Influenza A virus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.7Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PB2_I34A1 Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication (By similarity).

See Also

3cw4, resolution 2.70Å

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OCA
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