7u32: Difference between revisions

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'''Unreleased structure'''


The entry 7u32 is ON HOLD  until Paper Publication
==MVV cleaved synaptic complex (CSC) intasome at 3.4 A resolution==
<StructureSection load='7u32' size='340' side='right'caption='[[7u32]], [[Resolution|resolution]] 3.46&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7u32]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Visna/maedi_virus_EV1_KV1772 Visna/maedi virus EV1 KV1772] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7U32 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7U32 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.46&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7u32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7u32 OCA], [https://pdbe.org/7u32 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7u32 RCSB], [https://www.ebi.ac.uk/pdbsum/7u32 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7u32 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/POL_VILVK POL_VILVK] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.


Authors: Shan, Z., Pye, V.E., Cherepanov, P., Lyumkis, D.
==See Also==
 
*[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]]
Description: Cryo-EM reconstruction of the MVV cleaved synaptic complex intasome
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Pye, V.E]]
[[Category: Large Structures]]
[[Category: Shan, Z]]
[[Category: Synthetic construct]]
[[Category: Lyumkis, D]]
[[Category: Visna/maedi virus EV1 KV1772]]
[[Category: Cherepanov, P]]
[[Category: Cherepanov P]]
[[Category: Lyumkis D]]
[[Category: Pye VE]]
[[Category: Shan Z]]

Latest revision as of 13:56, 21 February 2024

MVV cleaved synaptic complex (CSC) intasome at 3.4 A resolutionMVV cleaved synaptic complex (CSC) intasome at 3.4 A resolution

Structural highlights

7u32 is a 20 chain structure with sequence from Visna/maedi virus EV1 KV1772 and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.46Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

POL_VILVK During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.

See Also

7u32, resolution 3.46Å

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